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Lysosomes as a therapeutic target

Lysosomes are membrane-bound organelles with roles in processes involved in degrading and recycling cellular waste, cellular signalling and energy metabolism. Defects in genes encoding lysosomal proteins cause lysosomal storage disorders, in which enzyme replacement therapy has proved successful. Gr...

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Detalles Bibliográficos
Autores principales: Bonam, Srinivasa Reddy, Wang, Fengjuan, Muller, Sylviane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097195/
https://www.ncbi.nlm.nih.gov/pubmed/31477883
http://dx.doi.org/10.1038/s41573-019-0036-1