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Correlates of protective immunity for Ebola vaccines: implications for regulatory approval by the animal rule
Ebola virus infection is a highly lethal disease for which there are no effective therapeutic or preventive treatments. Several vaccines have provided immune protection in laboratory animals, but because outbreaks occur unpredictably and sporadically, vaccine efficacy cannot be proven in human trial...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097244/ https://www.ncbi.nlm.nih.gov/pubmed/19369954 http://dx.doi.org/10.1038/nrmicro2129 |