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Gonococci cause immunosuppression by engaging a coinhibitory receptor on T lymphocytes
Gonococci that bind the coinhibitory receptor CEACAM1 appear to down-regulate the activation and proliferation of CD4(+) T cells. Such infection-induced immunosuppression helps explain why there is little specific immune response associated with gonococcal disease.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group US
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097558/ https://www.ncbi.nlm.nih.gov/pubmed/11875456 http://dx.doi.org/10.1038/ni0302-210 |