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MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2

Middle East respiratory syndrome coronavirus (MERS-CoV) causes sporadic zoonotic disease and healthcare-associated outbreaks in human. MERS is often complicated by acute respiratory distress syndrome (ARDS) and multi-organ failure(1,2). The high incidence of renal failure in MERS is a unique clinica...

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Detalles Bibliográficos
Autores principales: Yeung, Man-Lung, Yao, Yanfeng, Jia, Lilong, Chan, Jasper F. W., Chan, Kwok-Hung, Cheung, Kwok-Fan, Chen, Honglin, Poon, Vincent K. M., Tsang, Alan K. L., To, Kelvin K.W., Yiu, Ming-Kwong, Teng, Jade L. L., Chu, Hin, Zhou, Jie, Zhang, Qing, Deng, Wei, Lau, Susanna K. P., Lau, Johnson Y. N., Woo, Patrick C. Y., Chan, Tak-Mao, Yung, Susan, Zheng, Bo-Jian, Jin, Dong-Yan, Mathieson, Peter W., Qin, Chuan, Yuen, Kwok-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097571/
https://www.ncbi.nlm.nih.gov/pubmed/27572168
http://dx.doi.org/10.1038/nmicrobiol.2016.4