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OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids
Recent discoveries in the field of innate immunity have highlighted the existence of a family of nucleic acid-sensing proteins that have similar structural and functional properties. These include the well-known oligoadenylate synthase (OAS) family proteins and the recently identified OAS homologue...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097587/ https://www.ncbi.nlm.nih.gov/pubmed/25033909 http://dx.doi.org/10.1038/nri3719 |