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Engineering targeted viral vectors for gene therapy

To achieve therapeutic success, transfer vehicles for gene therapy must be capable of transducing target cells while avoiding impact on non-target cells. Despite the high transduction efficiency of viral vectors, their tropism frequently does not match the therapeutic need. In the past, this lack of...

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Detalles Bibliográficos
Autores principales: Waehler, Reinhard, Russell, Stephen J., Curiel, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097627/
https://www.ncbi.nlm.nih.gov/pubmed/17607305
http://dx.doi.org/10.1038/nrg2141