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Ace revisited: A new target for structure-based drug design

Current-generation angiotensin-converting enzyme (ACE) inhibitors are widely used for cardiovascular diseases, including high blood pressure, heart failure, heart attack and kidney failure, and have combined annual sales in excess of US $6 billion. However, the use of these ACE inhibitors, which wer...

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Detalles Bibliográficos
Autores principales: Acharya, K. Ravi, Sturrock, Edward D., Riordan, James F., Ehlers, Mario R. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097707/
https://www.ncbi.nlm.nih.gov/pubmed/14668810
http://dx.doi.org/10.1038/nrd1227