Cargando…

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation

ADP-ribosylation is a reversible post-translational modification with wide-ranging biological functions in all kingdoms of life. A variety of enzymes use NAD(+) to transfer either single or multiple ADP-ribose (ADPr) moieties onto distinct amino acid substrates, often in response to DNA damage or ot...

Descripción completa

Detalles Bibliográficos
Autores principales: Jankevicius, Gytis, Hassler, Markus, Golia, Barbara, Rybin, Vladimir, Zacharias, Martin, Timinszky, Gyula, Ladurner, Andreas G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097781/
https://www.ncbi.nlm.nih.gov/pubmed/23474712
http://dx.doi.org/10.1038/nsmb.2523