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Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond

In less than 20 years, the first selective type 5 phosphodiesterase inhibitor, sildenafil, has evolved from a potential anti-angina drug to an on-demand oral treatment for erectile dysfunction (Viagra), and more recently to a new orally active treatment for pulmonary hypertension (Revatio). Here we...

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Detalles Bibliográficos
Autores principales: Ghofrani, Hossein A., Osterloh, Ian H., Grimminger, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097805/
https://www.ncbi.nlm.nih.gov/pubmed/16883306
http://dx.doi.org/10.1038/nrd2030