Cargando…

Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets

The ubiquitin–proteasome system (UPS) and ubiquitin-like protein (UBL) conjugation pathways are integral to cellular protein homeostasis. The growing recognition of the fundamental importance of these pathways to normal cell function and in disease has prompted an in-depth search for small-molecule...

Descripción completa

Detalles Bibliográficos
Autores principales: Bedford, Lynn, Lowe, James, Dick, Lawrence R., Mayer, R. John, Brownell, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097807/
https://www.ncbi.nlm.nih.gov/pubmed/21151032
http://dx.doi.org/10.1038/nrd3321