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IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis
Psoriasis is an immune-mediated skin disorder associated with severe systemic comorbidities. Whereas IL-36 is a key disease driver, the pathogenic role of this cytokine has mainly been investigated in skin. Thus, its effects on systemic immunity and extracutaneous disease manifestations remain poorl...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097848/ https://www.ncbi.nlm.nih.gov/pubmed/31539532 http://dx.doi.org/10.1016/j.jid.2019.08.444 |