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PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner

Immune checkpoint blockade-based immunotherapy has become standard of care for multiple cancer types. However, the overall response rates among various cancer types still remain unsatisfactory. There is a pressing clinical need to identify combination therapies to improve efficacy of anticancer immu...

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Detalles Bibliográficos
Autores principales: Wu, Bogang, Sun, Xiujie, Yuan, Bin, Ge, Fei, Gupta, Harshita B., Chiang, Huai-Chin, Li, Jingwei, Hu, Yanfen, Curiel, Tyler J., Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097912/
https://www.ncbi.nlm.nih.gov/pubmed/32226299
http://dx.doi.org/10.7150/ijbs.42966