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Gen1 mutation caused kidney hypoplasia and defective ureter-bladder connections in mice

Limited genetic factors were uncovered for the development of congenital anomalies of the kidney and urinary tract (CAKUT). We previously reported that a Holliday junction resolvase Gen1 was essential for early metanephric development in mice. This comprehensive follow-up study focused on the roles...

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Detalles Bibliográficos
Autores principales: Wang, Xiaowen, Wang, Herui, Liu, Jiaojiao, Gong, Yinv, Zhang, Chi, Fang, Francia, Li, Aiguo, Wu, Xiaohui, Shen, Qian, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097914/
https://www.ncbi.nlm.nih.gov/pubmed/32226308
http://dx.doi.org/10.7150/ijbs.42855