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Bisdemethoxycurcumin Enhances the Sensitivity of Non-small Cell Lung Cancer Cells to Icotinib via Dual Induction of Autophagy and Apoptosis

Non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) wild-type is intrinsic resistance to EGFR-tyrosine kinase inhibitors (TKIs). In this study, we assessed whether the combination of bisdemethoxycurcumin (BDMC) and icotinib could surmount primary EGFR-TKI resistance in NS...

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Detalles Bibliográficos
Autores principales: Xiang, Min, Jiang, He-Guo, Shu, Yang, Chen, Yu-Jiao, Jin, Jun, Zhu, Yu-Min, Li, Mei-Yu, Wu, Jian-Nong, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097919/
https://www.ncbi.nlm.nih.gov/pubmed/32226300
http://dx.doi.org/10.7150/ijbs.40042