F2r negatively regulates osteoclastogenesis through inhibiting the Akt and NFκB signaling pathways

G-protein-coupled receptors (GPCRs) are pivotal drug targets for many diseases. Coagulation Factor II Thrombin Receptor (F2R) is an important member of GPCR family that is highly expressed in osteoclasts. However, the role of F2r in osteoclasts is still unclear. Here, to examine the functions of F2r...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Wang, He, Zhu, Guochun, Qian, Airong, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097923/
https://www.ncbi.nlm.nih.gov/pubmed/32226307
http://dx.doi.org/10.7150/ijbs.41867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097923/
https://www.ncbi.nlm.nih.gov/pubmed/32226307
http://dx.doi.org/10.7150/ijbs.41867

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