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Overexpression of DUSP6 enhances chemotherapy-resistance of ovarian epithelial cancer by regulating the ERK signaling pathway

Objective: DUSP6 is a negative regulator of the ERK signaling pathway and plays an important role in chemotherapy-resistance. Previously we showed that DUSP6 is overexpressed in ovarian cancer side population (SP) cells that possess cancer stem cell-like properties and are quiescent and chemotherapy...

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Detalles Bibliográficos
Autores principales: Gao, Yan, Li, Hui, Han, Qing, Li, Yuan, Wang, Tongxia, Huang, Cuiyu, Mao, Yiqing, Wang, Xi, Zhang, Qun, Tian, Junrui, Irwin, David M., Tan, Huanran, Guo, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097933/
https://www.ncbi.nlm.nih.gov/pubmed/32231719
http://dx.doi.org/10.7150/jca.37267