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Spin Label Scanning Reveals Likely Locations of β-Strands in the Amyloid Fibrils of the Ure2 Prion Domain

[Image: see text] In yeast, the formation of Ure2 fibrils underlies the prion state [URE3], in which the yeast loses the ability to distinguish good nitrogen sources from bad ones. The Ure2 prion domain is both necessary and sufficient for the formation of amyloid fibrils. Understanding the structur...

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Detalles Bibliográficos
Autores principales: Wang, Jingzhou, Park, Giovanna, Lee, Yoon Kyung, Nguyen, Matthew, San Fung, Tiffany, Lin, Tiffany Yuwen, Hsu, Frederick, Guo, Zhefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098000/
https://www.ncbi.nlm.nih.gov/pubmed/32226879
http://dx.doi.org/10.1021/acsomega.9b04358