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Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1

BACKGROUND: Current therapies for multiple myeloma (MM) are associated with toxicity and resistance, highlighting the need for novel effective therapeutics. Berberine (BBR), a botanical alkaloid derived from several Berberis medicinal plants, has exhibited anti-tumor effects, including against multi...

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Detalles Bibliográficos
Autores principales: Gu, Chunming, Yin, Zhao, Nie, Hong, Liu, Yanjun, Yang, Juhua, Huang, Guiping, Shen, Jianping, Chen, Liguo, Fei, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098108/
https://www.ncbi.nlm.nih.gov/pubmed/32213189
http://dx.doi.org/10.1186/s12915-020-00766-8