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Loss of receptor tyrosine kinase-like orphan receptor 2 impairs the osteogenesis of mBMSCs by inhibiting signal transducer and activator of transcription 3

BACKGROUND: Receptor tyrosine kinase-like orphan receptor 2 (Ror2) plays a key role in bone formation, but its signaling pathway is not completely understood. Signal transducer and activator of transcription 3 (Stat3) takes part in maintaining bone homeostasis. The aim of this study is to reveal the...

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Detalles Bibliográficos
Autores principales: Lei, Lizhen, Huang, Zhuwei, Feng, Jingyi, Huang, Zijing, Tao, Yiwei, Hu, Xiaoli, Zhang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098134/
https://www.ncbi.nlm.nih.gov/pubmed/32216811
http://dx.doi.org/10.1186/s13287-020-01646-2