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IGF-1C domain–modified hydrogel enhanced the efficacy of stem cells in the treatment of AMI

BACKGROUND: Due to the low survival rate of cell transplantation, stem cell has not been widely used in clinical treatment of acute myocardial infarction (AMI). In this study, we immobilized the C domain peptide of insulin-like growth factor-1 on chitosan (CS-IGF-1C) to obtain bioactive hydrogel. Th...

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Detalles Bibliográficos
Autores principales: Yao, Yong, Yang, Liang, Feng, Li-feng, Yue, Zhi-wei, Zhao, Nian-huan, Li, Zongjin, He, Zuo-xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098145/
https://www.ncbi.nlm.nih.gov/pubmed/32216819
http://dx.doi.org/10.1186/s13287-020-01637-3