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Sequential Infusion of Anti-CD22 and Anti-CD19 Chimeric Antigen Receptor T Cells for a Pediatric Ph-Like B-ALL Patient That Relapsed After CART-Cell and Haplo-HSCT Therapy: A Case Report and Review of Literature

Pediatric Philadelphia chromosome-like (Ph-like) acute B-lymphoblastic leukemia (B-ALL), a high-risk subset of B-ALL characterized by a gene expression profile similar to that of Ph-positive ALL, has extremely poor outcome after a relapse following autologous chimeric antigen receptor (CAR)-T and hap...

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Detalles Bibliográficos
Autores principales: Hua, Jingsheng, Qian, Weiqing, Wu, Xiaoxia, Zhou, Lili, Yu, Lei, Chen, Suning, Zhang, Jian, Qiu, Huiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098167/
https://www.ncbi.nlm.nih.gov/pubmed/32256082
http://dx.doi.org/10.2147/OTT.S235882