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Longitudinal Analyses of Cerebrospinal Fluid α-Synuclein in Prodromal and Early Parkinson’s Disease

BACKGROUND: Aggregation of α-synuclein is central to the pathophysiology of PD. Biomarkers related to α-synuclein may be informative for PD diagnosis/progression. OBJECTIVES: To analyze α-synuclein in CSF in drug-naïve PD, healthy controls, and prodromal PD in the Parkinson’s Progression Markers Ini...

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Detalles Bibliográficos
Autores principales: Mollenhauer, Brit, Caspell-Garcia, Chelsea J., Coffey, Christopher S., Taylor, Peggy, Singleton, Andy, Shaw, Leslie M., Trojanowski, John Q., Frasier, Mark, Simuni, Tanya, Iranzo, Alex, Oertel, Wolfgang, Siderowf, Andrew, Weintraub, Daniel, Seibyl, John, Toga, Arthur W., Tanner, Caroline M., Kieburtz, Karl, Chahine, Lana M., Marek, Kenneth, Galasko, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098385/
https://www.ncbi.nlm.nih.gov/pubmed/31361367
http://dx.doi.org/10.1002/mds.27806