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Genetic, Cellular, and Molecular Heterogeneity in Adrenals With Aldosterone-Producing Adenoma

Aldosterone-producing adenoma (APA) cause primary aldosteronism—the most frequent form of secondary hypertension. Somatic mutations in genes coding for ion channels and ATPases are found in APA and in aldosterone-producing cell clusters. We investigated the genetic, cellular, and molecular heterogen...

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Detalles Bibliográficos
Autores principales: De Sousa, Kelly, Boulkroun, Sheerazed, Baron, Stéphanie, Nanba, Kazutaka, Wack, Maxime, Rainey, William E., Rocha, Angélique, Giscos-Douriez, Isabelle, Meatchi, Tchao, Amar, Laurence, Travers, Simon, Fernandes-Rosa, Fabio L., Zennaro, Maria-Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott, Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098445/
https://www.ncbi.nlm.nih.gov/pubmed/32114847
http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.14177