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Nucleolar protein NOP2/NSUN1 suppresses HIV-1 transcription and promotes viral latency by competing with Tat for TAR binding and methylation
Recent efforts have been paid to identify previously unrecognized HIV-1 latency-promoting genes (LPGs) that can potentially be targeted for eradication of HIV-1 latent reservoirs. From our earlier orthologous RNAi screens of host factors regulating HIV-1 replication, we identified that the nucleolar...
Autores principales: | Kong, Weili, Biswas, Ayan, Zhou, Dawei, Fiches, Guillaume, Fujinaga, Koh, Santoso, Netty, Zhu, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098636/ https://www.ncbi.nlm.nih.gov/pubmed/32176734 http://dx.doi.org/10.1371/journal.ppat.1008430 |
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