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NMR Structure and Dynamics of TonB Investigated by Scar-Less Segmental Isotopic Labeling Using a Salt-Inducible Split Intein

The growing understanding of partially unfolded proteins increasingly points to their biological relevance in allosteric regulation, complex formation, and protein design. However, the structural characterization of disordered proteins remains challenging. NMR methods can access both the dynamics an...

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Detalles Bibliográficos
Autores principales: Ciragan, Annika, Backlund, Sofia M., Mikula, Kornelia M., Beyer, Hannes M., Samuli Ollila, O. H., Iwaï, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098700/
https://www.ncbi.nlm.nih.gov/pubmed/32266203
http://dx.doi.org/10.3389/fchem.2020.00136