Mitotic slippage is determined by p31(comet) and the weakening of the spindle-assembly checkpoint

Mitotic slippage involves cells exiting mitosis without proper chromosome segregation. Although degradation of cyclin B1 during prolonged mitotic arrest is believed to trigger mitotic slippage, its upstream regulation remains obscure. Whether mitotic slippage is caused by APC/C(CDC20) activity that...

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Detalles Bibliográficos
Autores principales: Lok, Tsun Ming, Wang, Yang, Xu, Wendy Kaichun, Xie, Siwei, Ma, Hoi Tang, Poon, Randy Y. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098889/
https://www.ncbi.nlm.nih.gov/pubmed/32029899
http://dx.doi.org/10.1038/s41388-020-1187-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098889/
https://www.ncbi.nlm.nih.gov/pubmed/32029899
http://dx.doi.org/10.1038/s41388-020-1187-6

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