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Involvement of the central nervous system in acute lymphoblastic leukemia: opinions on molecular mechanisms and clinical implications based on recent data

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. One of the major clinical challenges is adequate diagnosis and treatment of central nervous system (CNS) involvement in this disease. Intriguingly, there is little solid evidence on the mechanisms sustaining CNS disease in ALL....

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Detalles Bibliográficos
Autores principales: Lenk, Lennart, Alsadeq, Ameera, Schewe, Denis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098933/
https://www.ncbi.nlm.nih.gov/pubmed/31970588
http://dx.doi.org/10.1007/s10555-020-09848-z