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Insights into the prenatal origin of childhood acute lymphoblastic leukemia

Pediatric acute lymphoblastic leukemia (ALL) is defined by recurrent chromosomal aberrations including hyperdiploidy and chromosomal translocations. Many of these aberrations originate in utero and the cells transform in early childhood through acquired secondary mutations. In this review, we will d...

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Detalles Bibliográficos
Autores principales: Hein, Daniel, Borkhardt, Arndt, Fischer, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098935/
https://www.ncbi.nlm.nih.gov/pubmed/31902036
http://dx.doi.org/10.1007/s10555-019-09841-1