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Insights into the prenatal origin of childhood acute lymphoblastic leukemia
Pediatric acute lymphoblastic leukemia (ALL) is defined by recurrent chromosomal aberrations including hyperdiploidy and chromosomal translocations. Many of these aberrations originate in utero and the cells transform in early childhood through acquired secondary mutations. In this review, we will d...
Autores principales: | Hein, Daniel, Borkhardt, Arndt, Fischer, Ute |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098935/ https://www.ncbi.nlm.nih.gov/pubmed/31902036 http://dx.doi.org/10.1007/s10555-019-09841-1 |
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