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Trypanosoma cruzi-Infected Human Macrophages Shed Proinflammatory Extracellular Vesicles That Enhance Host-Cell Invasion via Toll-Like Receptor 2

Extracellular vesicles (EVs) shed by trypomastigote forms of Trypanosoma cruzi have the ability to interact with host tissues, increase invasion, and modulate the host innate response. In this study, EVs shed from T. cruzi or T.cruzi-infected macrophages were investigated as immunomodulatory agents...

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Detalles Bibliográficos
Autores principales: Cronemberger-Andrade, André, Xander, Patrícia, Soares, Rodrigo Pedro, Pessoa, Natália Lima, Campos, Marco Antônio, Ellis, Cameron C., Grajeda, Brian, Ofir-Birin, Yifat, Almeida, Igor Correia, Regev-Rudzki, Neta, Torrecilhas, Ana Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098991/
https://www.ncbi.nlm.nih.gov/pubmed/32266161
http://dx.doi.org/10.3389/fcimb.2020.00099