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A Mendelian Randomization Analysis to Expose the Causal Effect of IL-18 on Osteoporosis Based on Genome-Wide Association Study Data

Accumulating evidence showed that Interleukin (IL) level is associated with Osteoporosis. Whereas, most of these associations are based on observational studies. Thus, their causality was still unclear. Mendelian randomization (MR) is a widely used statistical framework that uses genetic instrumenta...

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Detalles Bibliográficos
Autores principales: Kou, Ni, Zhou, Wenyang, He, Yuzhu, Ying, Xiaoxia, Chai, Songling, Fei, Tao, Fu, Wenqi, Huang, Jiaqian, Liu, Huiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099043/
https://www.ncbi.nlm.nih.gov/pubmed/32266232
http://dx.doi.org/10.3389/fbioe.2020.00201