Activity-dependent isomerization of Kv4.2 by Pin1 regulates cognitive flexibility

Voltage-gated K(+) channels function in macromolecular complexes with accessory subunits to regulate brain function. Here, we describe a peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1)-dependent mechanism that regulates the association of the A-type K(+) channel subunit Kv4.2 with its...

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Detalles Bibliográficos
Autores principales: Hu, Jia–Hua, Malloy, Cole, Tabor, G. Travis, Gutzmann, Jakob J., Liu, Ying, Abebe, Daniel, Karlsson, Rose-Marie, Durell, Stewart, Cameron, Heather A., Hoffman, Dax A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099064/
https://www.ncbi.nlm.nih.gov/pubmed/32218435
http://dx.doi.org/10.1038/s41467-020-15390-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099064/
https://www.ncbi.nlm.nih.gov/pubmed/32218435
http://dx.doi.org/10.1038/s41467-020-15390-x

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