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The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

Estrogens and progesterone control breast development and carcinogenesis via their cognate receptors expressed in a subset of luminal cells in the mammary epithelium. How they control the extracellular matrix, important to breast physiology and tumorigenesis, remains unclear. Here we report that bot...

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Detalles Bibliográficos
Autores principales: Ataca, Dalya, Aouad, Patrick, Constantin, Céline, Laszlo, Csaba, Beleut, Manfred, Shamseddin, Marie, Rajaram, Renuga Devi, Jeitziner, Rachel, Mead, Timothy J., Caikovski, Marian, Bucher, Philipp, Ambrosini, Giovanna, Apte, Suneel S., Brisken, Cathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099066/
https://www.ncbi.nlm.nih.gov/pubmed/32218432
http://dx.doi.org/10.1038/s41467-020-15357-y