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A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo
Near-infrared (NIR) fluorescent probes are among the most attractive chemical tools for biomedical imaging. However, their in vivo applications are hindered by albumin binding, generating unspecific fluorescence that masks the specific signal from the analyte. Here, combining experimental and dockin...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099068/ https://www.ncbi.nlm.nih.gov/pubmed/32218438 http://dx.doi.org/10.1038/s41467-020-15323-8 |