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A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo

Near-infrared (NIR) fluorescent probes are among the most attractive chemical tools for biomedical imaging. However, their in vivo applications are hindered by albumin binding, generating unspecific fluorescence that masks the specific signal from the analyte. Here, combining experimental and dockin...

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Detalles Bibliográficos
Autores principales: Xing, Panfei, Niu, Yiming, Mu, Ruoyu, Wang, Zhenzhen, Xie, Daping, Li, Huanling, Dong, Lei, Wang, Chunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099068/
https://www.ncbi.nlm.nih.gov/pubmed/32218438
http://dx.doi.org/10.1038/s41467-020-15323-8