Transformation Foci in IDH1-mutated Gliomas Show STAT3 Phosphorylation and Downregulate the Metabolic Enzyme ETNPPL, a Negative Regulator of Glioma Growth

IDH1-mutated gliomas are slow-growing brain tumours which progress into high-grade gliomas. The early molecular events causing this progression are ill-defined. Previous studies revealed that 20% of these tumours already have transformation foci. These foci offer opportunities to better understand m...

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Detalles Bibliográficos
Autores principales: Leventoux, N., Augustus, M., Azar, S., Riquier, S., Villemin, J. P., Guelfi, S., Falha, L., Bauchet, L., Gozé, C., Ritchie, W., Commes, T., Duffau, H., Rigau, V. , Hugnot, J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099072/
https://www.ncbi.nlm.nih.gov/pubmed/32218467
http://dx.doi.org/10.1038/s41598-020-62145-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099072/
https://www.ncbi.nlm.nih.gov/pubmed/32218467
http://dx.doi.org/10.1038/s41598-020-62145-1

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