Evaluating the potential of hyperpolarised [1-(13)C] L-lactate as a neuroprotectant metabolic biosensor for stroke

Cerebral metabolism, which can be monitored by magnetic resonance spectroscopy (MRS), changes rapidly after brain ischaemic injury. Hyperpolarisation techniques boost (13)C MRS sensitivity by several orders of magnitude, thereby enabling in vivo monitoring of biochemical transformations of hyperpola...

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Detalles Bibliográficos
Autores principales: Hyacinthe, Jean-Noël, Buscemi, Lara, Lê, Thanh Phong, Lepore, Mario, Hirt, Lorenz, Mishkovsky, Mor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099080/
https://www.ncbi.nlm.nih.gov/pubmed/32218474
http://dx.doi.org/10.1038/s41598-020-62319-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099080/
https://www.ncbi.nlm.nih.gov/pubmed/32218474
http://dx.doi.org/10.1038/s41598-020-62319-x

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