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Evaluating the potential of hyperpolarised [1-(13)C] L-lactate as a neuroprotectant metabolic biosensor for stroke
Cerebral metabolism, which can be monitored by magnetic resonance spectroscopy (MRS), changes rapidly after brain ischaemic injury. Hyperpolarisation techniques boost (13)C MRS sensitivity by several orders of magnitude, thereby enabling in vivo monitoring of biochemical transformations of hyperpola...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099080/ https://www.ncbi.nlm.nih.gov/pubmed/32218474 http://dx.doi.org/10.1038/s41598-020-62319-x |