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Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells

Salmonella typhimurium VNP-20009 (VNP) is a non-pathogenic attenuated strain, which, as a facultative anaerobe, preferentially accumulates in hypoxic regions of solid tumors. Here, VNP was utilized as a delivery vehicle of the anti-tumor protein Lipidated azurin, Laz, which is produced by the mening...

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Detalles Bibliográficos
Autores principales: Mansour, Manar, Ismail, Shehab, Abou-Aisha, Khaled
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099546/
https://www.ncbi.nlm.nih.gov/pubmed/32221741
http://dx.doi.org/10.1186/s13568-020-00995-8