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Dual-functioning antimalarials that inhibit the chloroquine-resistance transporter

Malaria remains a major international health challenge. Resistance to a number of existing drugs and evidence of the emergence of artemisinin resistance has emphasized the need for new antimalarials. A new approach has been the preparation of dual-function compounds that include a chloroquine-like a...

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Detalles Bibliográficos
Autores principales: Egan, Timothy J, Kuter, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099626/
https://www.ncbi.nlm.nih.gov/pubmed/23534360
http://dx.doi.org/10.2217/fmb.13.18