ExoU-induced redox imbalance and oxidative stress in airway epithelial cells during Pseudomonas aeruginosa pneumosepsis

ExoU is a potent proinflammatory toxin produced by Pseudomonas aeruginosa, a major agent of severe lung infection and sepsis. Because inflammation is usually associated with oxidative stress, we investigated the effect of ExoU on free radical production and antioxidant defense mechanisms during the...

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Detalles Bibliográficos
Autores principales: da Cunha, Luiz Gonzaga, Ferreira, Miriam Francisca, de Moraes, João Alfredo, Reis, Patricia Alves, Castro-Faria-Neto, Hugo Caire, Barja-Fidalgo, Christina, Plotkowski, Maria-Cristina, Saliba, Alessandra Mattos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100071/
https://www.ncbi.nlm.nih.gov/pubmed/25904542
http://dx.doi.org/10.1007/s00430-015-0418-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100071/
https://www.ncbi.nlm.nih.gov/pubmed/25904542
http://dx.doi.org/10.1007/s00430-015-0418-x

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