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ExoU-induced redox imbalance and oxidative stress in airway epithelial cells during Pseudomonas aeruginosa pneumosepsis
ExoU is a potent proinflammatory toxin produced by Pseudomonas aeruginosa, a major agent of severe lung infection and sepsis. Because inflammation is usually associated with oxidative stress, we investigated the effect of ExoU on free radical production and antioxidant defense mechanisms during the...
Autores principales: | da Cunha, Luiz Gonzaga, Ferreira, Miriam Francisca, de Moraes, João Alfredo, Reis, Patricia Alves, Castro-Faria-Neto, Hugo Caire, Barja-Fidalgo, Christina, Plotkowski, Maria-Cristina, Saliba, Alessandra Mattos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100071/ https://www.ncbi.nlm.nih.gov/pubmed/25904542 http://dx.doi.org/10.1007/s00430-015-0418-x |
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