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RNAi Therapy for HIV Infection: Principles and Practicalities

Inside eukaryotic cells, small RNA duplexes, called small interfering RNAs (siRNAs), activate a conserved RNA interference (RNAi) pathway which leads to specific degradation of complementary target mRNAs through base-pairing recognition. As with other viruses, studies have shown that replication of...

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Detalles Bibliográficos
Autores principales: Bennasser, Yamina, Yeung, Man Lung, Jeang, Kuan-Teh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100089/
https://www.ncbi.nlm.nih.gov/pubmed/17263586
http://dx.doi.org/10.2165/00063030-200721010-00003