Derivatives of activated H-ras lacking C-terminal lipid modifications retain transforming ability if targeted to the correct subcellular location

To examine the ability of ras to activate signal transduction pathways in the absence of lipid modifications, fusion proteins were constructed that target ras(WT) or activated ras(61L) to cellular membranes as integral membrane proteins, using the first transmembrane domain of the E1 protein of avia...

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Detalles Bibliográficos
Autores principales: Hart, Kristen C, Donoghue, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100284/
https://www.ncbi.nlm.nih.gov/pubmed/9050994
http://dx.doi.org/10.1038/sj.onc.1200908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100284/
https://www.ncbi.nlm.nih.gov/pubmed/9050994
http://dx.doi.org/10.1038/sj.onc.1200908

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