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Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

Since 2002, beta coronaviruses (CoV) have caused three zoonotic outbreaks, SARS-CoV in 2002–2003, MERS-CoV in 2012, and the newly emerged SARS-CoV-2 in late 2019. However, little is currently known about the biology of SARS-CoV-2. Here, using SARS-CoV-2 S protein pseudovirus system, we confirm that...

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Detalles Bibliográficos
Autores principales: Ou, Xiuyuan, Liu, Yan, Lei, Xiaobo, Li, Pei, Mi, Dan, Ren, Lili, Guo, Li, Guo, Ruixuan, Chen, Ting, Hu, Jiaxin, Xiang, Zichun, Mu, Zhixia, Chen, Xing, Chen, Jieyong, Hu, Keping, Jin, Qi, Wang, Jianwei, Qian, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100515/
https://www.ncbi.nlm.nih.gov/pubmed/32221306
http://dx.doi.org/10.1038/s41467-020-15562-9