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May the Force Not Be With You During Culture: Eliminating Mechano-Associated Feedback During Culture Preserves Cultured Atrial and Pacemaker Cell Functions

Cultured cardiomyocytes have been shown to possess significant potential as a model for characterization of mechano-Ca(2+), mechano-electric, and mechano-metabolic feedbacks in the heart. However, the majority of cultured cardiomyocytes exhibit impaired electrical, mechanical, biochemical, and metab...

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Detalles Bibliográficos
Autores principales: Kirschner Peretz, Noa, Segal, Sofia, Yaniv, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100534/
https://www.ncbi.nlm.nih.gov/pubmed/32265724
http://dx.doi.org/10.3389/fphys.2020.00163