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VEGF-C-driven lymphatic drainage enables brain tumor immunosurveillance

Immune surveillance against pathogens and tumors in the central nervous system (CNS) is thought to be limited due to the lack of lymphatic drainage. However, recent characterization of the meningeal lymphatic network sheds new light on previously unappreciated ways of eliciting immune response to an...

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Detalles Bibliográficos
Autores principales: Song, Eric, Mao, Tianyang, Dong, Huiping, Boisserand, Ligia Simoes Braga, Antila, Salli, Bosenberg, Marcus, Alitalo, Kari, Thomas, Jean-Leon, Iwasaki, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100608/
https://www.ncbi.nlm.nih.gov/pubmed/31942068
http://dx.doi.org/10.1038/s41586-019-1912-x