Cargando…

The structure of the cohesin ATPase elucidates the mechanism of SMC–kleisin ring opening

Genome regulation requires control of chromosomal organization by SMC–kleisin complexes. The cohesin complex contains the Smc1 and Smc3 subunits which associate with the kleisin Scc1 to form a ring-shaped complex that can topologically engage chromatin to regulate chromatin structure. Release from c...

Descripción completa

Detalles Bibliográficos
Autores principales: Muir, Kyle W., Li, Yan, Weis, Felix, Panne, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100847/
https://www.ncbi.nlm.nih.gov/pubmed/32066964
http://dx.doi.org/10.1038/s41594-020-0379-7