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Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma

BACKGROUND: Temozolomide (TMZ) has been the standard-of-care chemotherapy for glioblastoma (GBM) patients for more than a decade. Despite this long time in use, significant questions remain regarding how best to optimize TMZ therapy for individual patients. Understanding the relationship between TMZ...

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Detalles Bibliográficos
Autores principales: Massey, Susan Christine, White, Haylye, Whitmire, Paula, Doyle, Tatum, Johnston, Sandra K., Singleton, Kyle W., Jackson, Pamela R., Hawkins-Daarud, Andrea, Bendok, Bernard R., Porter, Alyx B., Vora, Sujay, Sarkaria, Jann N., Hu, Leland S., Mrugala, Maciej M., Swanson, Kristin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100932/
https://www.ncbi.nlm.nih.gov/pubmed/32218600
http://dx.doi.org/10.1371/journal.pone.0230492