Nanoparticle-based targeted delivery of pentagalloyl glucose reverses elastase-induced abdominal aortic aneurysm and restores aorta to the healthy state in mice

AIM: Abdominal aortic aneurysms (AAA) is a life-threatening weakening and expansion of the abdominal aorta due to inflammatory cell infiltration and gradual degeneration of extracellular matrix (ECM). There are no pharmacological therapies to treat AAA. We tested the hypothesis that nanoparticle (NP...

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Detalles Bibliográficos
Autores principales: Dhital, Saphala, Vyavahare, Naren R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100957/
https://www.ncbi.nlm.nih.gov/pubmed/32218565
http://dx.doi.org/10.1371/journal.pone.0227165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100957/
https://www.ncbi.nlm.nih.gov/pubmed/32218565
http://dx.doi.org/10.1371/journal.pone.0227165

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