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Probenecid treatment improves outcomes in a novel mouse model of peripartum cardiomyopathy
Probenecid has been used for decades in the treatment of gout but recently has also been found to improve outcomes in patients with heart failure via stimulation of the transient receptor potential vanilloid 2 (TRPV2) channel in cardiomyocytes. This study tested the use of probenecid on a novel mous...
Autores principales: | Onusko, Evan, McDermott, Michael R., Robbins, Nathan, Liu, Guansheng, Kranias, Evangelia G., Rubinstein, Jack, Koch, Sheryl E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100971/ https://www.ncbi.nlm.nih.gov/pubmed/32218573 http://dx.doi.org/10.1371/journal.pone.0230386 |
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